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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
34.85
Human Site:
S525
Identified Species:
58.97
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
S525
V
H
M
G
L
L
K
S
E
D
K
V
K
A
I
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
S525
V
H
M
G
L
L
K
S
E
D
K
V
K
A
I
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
S579
A
H
M
G
L
L
K
S
E
D
K
V
K
A
I
Dog
Lupus familis
XP_538355
1323
142434
S525
V
H
M
G
L
L
K
S
E
D
K
I
K
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
S527
I
H
M
G
L
L
K
S
E
D
K
I
K
A
I
Rat
Rattus norvegicus
NP_001012199
431
46388
E370
E
D
E
D
E
D
E
E
G
E
D
D
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
S527
V
H
M
G
L
L
K
S
E
D
K
I
K
A
I
Chicken
Gallus gallus
NP_001006237
580
63057
S518
I
H
M
G
L
L
K
S
E
E
K
I
K
A
V
Frog
Xenopus laevis
O13066
580
62889
S518
V
Q
M
G
L
L
K
S
E
D
K
M
K
T
I
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
S504
V
M
V
G
L
L
K
S
E
D
K
L
K
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
Q535
D
Y
A
I
K
T
K
Q
E
T
R
V
L
N
Y
Honey Bee
Apis mellifera
XP_395378
580
63771
D510
L
G
L
I
K
A
E
D
K
N
S
G
K
I
D
Nematode Worm
Caenorhab. elegans
P34342
960
105635
A822
D
E
D
D
D
E
E
A
E
I
Q
I
I
D
N
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
L326
P
H
L
T
L
L
D
L
N
G
N
N
I
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
93.3
73.3
80
66.6
N.A.
20
6.6
6.6
20
P-Site Similarity:
100
100
93.3
100
N.A.
100
20
N.A.
100
100
86.6
86.6
N.A.
33.3
40
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
0
8
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
8
15
8
8
8
8
0
58
8
8
0
15
8
% D
% Glu:
8
8
8
0
8
8
22
8
79
15
0
0
8
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
65
0
0
0
0
8
8
0
8
0
8
0
% G
% His:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
15
0
0
0
0
0
8
0
36
15
8
50
% I
% Lys:
0
0
0
0
15
0
72
0
8
0
65
0
72
0
0
% K
% Leu:
8
0
15
0
72
72
0
8
0
0
0
8
8
0
0
% L
% Met:
0
8
58
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
8
8
0
8
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
65
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
0
0
8
0
0
0
8
0
% T
% Val:
43
0
8
0
0
0
0
0
0
0
0
29
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _